^nS^ST™"}  Gleanings  from  the  German  Journals.  5^3 
MISTURA  GLYCYRRHIZAE  COMPOSITA. 
By  Walter  L.  Stephen. 
The  following  method  of  making  mistura  glycyrrhizae  comp.  yields 
a  preparation  affording  no  sediment  whatever,  as  proven  by  my 
experiments  : 
R.    Acaciae  pulv.,  §  ss. 
Ext.  glycyrrhizae  pulv.,  !§  ss. 
Sacchari  pulv.,  ^  ss. 
Spts.  aeth.  nit.,  f  J  ss. 
Vin.  antimonii,  f  3  i 
Tr.  opii  camph.,  ii 
Aquae  dest,  f^xii 
Having  mixed  well  the  powders,  add  6  fluid  ounces  of  water 
gradually  and  rub  to  a  paste.  Place  this  in  an  evaporating  dish 
and  heat  until  perfectly  fluid.  Add  the  sweet  spirit  of  nitre,  wine  of 
antimony  and  paregoric  and  enough  water  to  make  the  required 
amount.  The  heat  employed  destroys  molecular  aggregation  other- 
wise not  effected  and  results  in  better  and  perfect  diffusion  of  the 
solid  substances,  which  gives  a  product  devoid  of  sediment. 
Philadelphia,  October  26,  1892. 
GLEANINGS  FROM  THE  GERMAN  JOURNALS. 
By  Frank  X.  Moerk,  Ph.G. 
Syrupus  Granati  covticis. — 100  gm.  of  the  finely  powdered  bark 
are  boiled  for  one  hour  with  dilute  alcohol,  sp.  gr.  0-892,  using  a 
reflux  condenser  ;  after  cooling,  the  drug  is  exhausted  with  dilute 
alcohol,  and  the  percolate,  after  the  addition  of  60  gm.  sugar,  is  evap- 
orated on  a  water-bath  to  100  gm.  Alkaloidal  assays  of  this  prep- 
aration freshly  made  and  after  the  expiration  of  two  years  gave 
almost  identical  results.  The  precipitate  produced  upon  standing 
contained  no  alkaloid,  but  appeared  to  consist  almost  entirely  of  tan- 
nin. Owing  to  the  deterioration  of  the  dried  bark  and  the  stability 
of  the  syrup,  it  is  suggested  that  the  syrup  be  made  in  such  places 
as  abound  in  the  production  of  the  drug.  The  presence  of  23  per 
cent,  tannin  in  the  bark  imparts  to  the  syrup  an  unpleasant,  astrin- 
gent taste  ;  endeavors  to  manufacture  a  more  palatable  preparation 
led  to  the  following  formula  :  The  powdered  bark  is  digested  with 
the  necessary  quantity  of  water  for  twelve  hours  in  a  water-bath  ; 
alter  cooling,  50  per  cent,  slaked  lime  is  incorporated,  allowed  to 
