Am.  Jour.  Pharm.  | 
January,  1909.  f 
Analysis  of  Headache  Mixtures. 
3 
yields  from  four  to  six  rootlets  that  can  be  used  for  propagation.  In 
late  years  I  have  not  found  it  necessary  to  propagate  from  the  seed 
at  aft;  always  using  last  year's  roots.  It  saves  much  labor  and  always 
assures  a  good  crop.  The  plants  which  are  raised  from  the  roots 
direct  sometimes  reach  a  height  of  about  65  inches  if  the  season  is 
neither  too  dry  nor  too  wet.  Some  of  the  plants  will  weigh  five 
pounds,  about  sixty  per  cent,  in  weight  being  lost  by  drying. 
The  yield  of  one  acre  of  Belladonna  is  from  six  to  eight  thousand 
pounds.  If  the  plants  are  propagated  from  the  roots,  as  described, 
some  of  the  seeds  from  the  hardiest  looking  plants  should  be  col- 
lected each  year  and  germinated  the  following  spring  for  the  pro- 
duction of  a  new  stock  of  plants.  There  will  be  no  difficulty  expe- 
rienced if  the  seeds  of  cultivated  plants  are  used,  and  care  taken  not 
to  bury  the  seeds  too  deep  in  the  soil. 
Insects  do  not  give  much  trouble  in  the  raising  of  Belladonna. 
Sometimes,  however,  the  young  plants  wither  and  turn  black,  due  to 
a  worm  which  attacks  the  roots.  This  year  the  yield  of  a  quarter  of 
an  acre  amounted  to  eighteen  hundred  pounds.  The  plants  did  not 
reach  a  height  over  40  inches,  due  to  the  dry  season. 
Among  other  plants  which  I  have  under  cultivation  I  may  mention 
the  following :  Hyoscyamus,  Matricaria,  Pulsatilla,  Conium,  Taba- 
cum,  Calendula,  Passiflora,  Hydrastis,  Inula,  Digitalis,  Absinthium, 
Arnica,  and  Echinacea. 
ANALYSIS  OF  HEADACHE  MIXTURES.* 
By  Dr.  W.  O.  Emery. 
•  The  advent  of  the  Food  and  Drugs  Act  of  June  30,  1906,  has 
rendered  necessary  among  other  things  the  establishment  of  suf- 
ficient data  upon  which  reliable  methods  could  be  based  for  the 
quantitative  estimation  of  those  drugs  inhibited  by  this  Act.  In  this 
connection  it  was  thought  desirable  if  not  equally  imperative  to  in- 
clude in  such  investigations  all  other  active  drug  principles  in  so  far 
as  it  might  be  found  possible  to  effect  satisfactory  determination 
of  same. 
*  Read  ,at  a  stated  meeting  of  the  City  of  Washington  Branch  of  the 
American  Pharmaceutical  Association,  December  14,  1908. 
