The  Canadian  Formulary. 
(  Am.  Jour.  Pharcu. 
\    January,  1909. 
Formula  76,  for  Sodium  of  Carmine,  N.  F.,  1906,  shows  a  de- 
crease of  carmine  from  65  G111.  to  60  Gm.,  and  of  solution  of  am- 
monia and  glycerin  from  365  c.c.  each  to  350  c.c.  each,  the  quantity 
of  the  end  product  remaining  the  same. 
Formula  No.  80,  for  Solution  of  Saccharin,  contains  a  slightly 
larger  amount  of  saccharin  and  a  smaller  amount  of  sodium  bicar- 
bonate than  the  N.  F.  solution,  although  the  same  statement  is  made 
as  to  strength,  L  c,  four  grains  to  the  fluidrachm. 
Formula  87,  for  Solution  of  Sodium  Hydroxide,  is  stated  to  be  the 
same  as  the  U.  S.  P.,  1905.  but  instead  of  using  5.6  Gm.  of  sodium 
hydroxide,  so  as  to  give  a  strength  of  5  per  cent,  absolute  sodium 
hydroxide,  the  formula  calls  for  5  Gm.  in  100,  which  would  give  a 
strength  of  4.50  per  cent. 
Formula  95,  for  Pepsinum  Saccharatum,  contains  a  statement  that 
it  is  U.  S.  P.,  1905.  This  is  an  error,  as  it  was  dismissed  from  the 
last  revision  and  is  now  in  the  appendix  of  the  X.  F. 
Formula  122,  for  Aromatic  Syrup  of  Blackberry,  X.  F.,  1906, 
shows  a  slight  alteration  in  the  amounts  of  blackberry  root  bark, 
cinnamon  and  nutmeg,  but  no  alteration  in  the  amounts  of  cloves, 
allspice  or  sugar. 
No.  135,  for  Compound  Tincture  of  Cudbear,  shows  a  change  in 
the  amount  of  cudbear  from  16.5  Gm.  to  17  Gm.,  the  other  constitu- 
ents remaining  the  same. 
Formula  147  for  Wine  of  Coca,  said  to  be  U.  S.  P.,  1905,  has  the 
amount  of  sugar  increased  from  65  to  75  Gm.,  the  other  constitu- 
ents remaining  the  same. 
A  few  comments  might  also  be  made  upon  other  preparations 
which  are  not  stated  to  conform  to  any  given  authority.  Formula 
132,  for  Elixir  of  Papain,  is  presumably  a  digestive  elixir,  and  the 
presence  of  1.15  Gm.  of  saccharin  to  1000  c.c.  would  certainly  be 
of  doubtful  value,  if  not  actually  harmful.  It  would  certainly  have 
an  inhibiting  effect  upon  the  digestive  power  of  papain,  which  is 
feeble  at  its  best. 
X'o.  43,  Elixir  of  Terpin  Hydrate  and  Heroin;  among  the  ingre- 
dients are  noted  16  c.c.  of  brandy  in  1000  c.c.  As  this  could  hardly 
have  any  flavoring  effect  in  the  presence  of  4  c.c.  of  tincture  of 
vanilla,  and  as  it  could  hardly  be  used  for  its  alcoholic  value,  there 
being  375  c.c.  of  alcohol  already  present,  the  reason  for  the  addi- 
tion of  this  small  amount  of  brandy  is  not  apparent. 
Formula  Xo.  49,  for  Essence  of  Lemon,  gives  a  strength  of  2.5 
