Am.  Jour.  Pharm. 
July,  1909. 
} 
Syrups. 
313 
syrup  of  hypophosphites  made  these  clear  and  permanent  for  at 
least  a  year.    We  suggest  that  in  the  syrup  of  hypophosphites  and 
directs  its  addition  to  the  extent  of  not  more  than  100  ex.  in  a  litre. 
Incidentally  in  these  experiments  we  have  tried  some  of  the 
suggestions  of  other  writers  and  these  may  be  referred  to  in  the 
comments  and  reports  on  the  individual  syrups.  The  formulas 
offered  are  the  results  of  many  experiments ;  the  details  of  those 
unsatisfactory,  as  a  rule,  are  omitted, 
Syrupus  Amygdala  U.S. P. — The  U.S. P.  VIII  has  discarded  the 
formula  for  syrup  of  almonds  made  from  an  emulsion  of  almonds, 
although  this  method  is  still  retained  in  the  foreign  Pharmacopoeias. 
The  present  formula  is  simply  a  very  dilute  bitter  almond  and 
orange  flower  syrup  and  will  not  keep  indefinitely.  The  small 
amount  of  spirit  of  bitter  almond  directed  is  insufficient  to  act  as 
a  preservative  and  is  itself  soon  oxidized.  We  recommend  in  this 
syrup  that  the  spirit  of  bitter  almond  be  increased  to  20  c.c.  in  the 
litre  and  that  stronger  orange  flower  water  be  used,  also  that 
extemporaneous  preparation  be  directed. 
Syrupus  Aurantii  U.S. P. — The  present  official  method  is  de- 
structive of  the  fine  aroma  of  the  tincture  of  sweet  orange  peel  and 
leaves  with  the  magnesium  carbonate  a  large  proportion  of  the  flav:r, 
We  recommend  the  following  as  an  improvement,  retaining  all  of 
the  flavor  of  the  tincture  and  not  exposing  this  to  oxidation. 
Tincture  of  sweet  orange  peel   50  c.c. 
Citric  acid    5  Gms. 
Glycerin   100  c.c. 
Syrup,  a  sufficient  quantity  to  make   1000  c.c. 
Dissolve  the  citric  acid  in  500  c.c.  of  syrup  mixed  with  the 
glycerin.  Gradually  add  the  tincture  of  sweet  orange  peel,  shaking 
after  each  addition,  then  add  sufficient  syrup  to  make  1000  c.c.  The 
improvement  in  -  flavor  over  the  present  U.S. P.  formula  is  marked 
and  the  opale.c  is  scarcely  perceptible. 
Syrupus  Aurantii  Florum  U.S. P. — Stronger  orange  flower 
water  should  be  directed  in  this  formula. 
Syrupus  Ipecacuanha  U.S. P. — This  syrup  can  be  very  readily 
prepared  direct  from  the  powdered  drug  without  any  deviation  of 
the  ofi  cial  strength  or  ingredients.  The  following  is  the  improved 
formula  proposed: 
the  compound  syrup  of 
■.osphites  that  the  Pharmacopoeia 
