314 
Syrups. 
{ 
Am.  Jour.  Pharm. 
July,  1909. 
Powdered  ipecac 
Acetic  acid   
Glycerin   
Sugar   
70  Gms. 
10  c.c. 
100  c.c. 
750  Gms. 
Water,  a  sufficient  quantity. 
Percolate  the  ipecac  with  a  mixture  of  the  acetic  acid,  glycerin, 
and  290  c.c.  of  water,  and  then  continue  the  percolation  with  water 
till  600  c.c.  of  percolate  is  obtained.  In  this  dissolve  the  sugar,  add 
sufficient  water  to  make  the  product  measure  1000  c.c. 
Syrupus  Kramerije  U.S. P.— The  official  formula  illustrates  the 
use  of  fluidextracts  to  the  limit  and  despite  the  relatively  large 
amount  of  alcohol  present  does  not  keep  well.  E.  Fullerton -Cook  3 
characterizes  "  this  syrup  as  pharmaceutical^  unsatisfactory.  .  .  . 
When  the  fluidextract  and  syrup  are  mixed,  a  coagulated  mass, 
almost  too  thick  to  pour,  results.  As  this  syrup  stands  it  separates 
into  two  layers,  a  clear,  dark-reddish  liquid  above,  and  a  cloudy 
portion  occupying  about  three-fourths  of  the  bottle  with  a  heavy- 
precipitate  at  the  bottom." 
For  this  we  submit  the  following  formulas : 
Krameria  (No.  20  powder)   450  Gms. 
Glycerin    225  c.c. 
Sugar   650  Gms. 
Water,  a  sufficient  quantity. 
Mix  the  glycerin  with  675  c.c.  of  water  and  percolate  the  kra- 
meria with  this  mixture,  and  then  continue  percolation  with  water 
till  the  drug  is  extracted,  evaporate  the  percolate  to  650  c.c,  and 
in  this  while  still  warm  dissolve  the  sugar.  Strain  the  liquid  and 
add  sufficient  distilled  water  to  make  1000  c.c.  of  product. 
As  an  alternative  formula : 
Fluidglycerate  of  krameria    450  c.c. 
Syrup    550  c.c. 
Either  of  these  formulas  yields  a  clear  liquid  which  keeps  fairly 
well  without  gelatinizing  or  precipitating. 
Syrupus  Lactucarii  U.S. P. — To  obtain  a  pharmaceutically  satis- 
factory product  by  the  official  method  requires  a  perfect  tincture  of 
lactucarium.    The  latter  is  difficult  to  prepare,  and  not  infrequently 
Mix. 
3  Proceedings  Amer.  Phar.  Assn.,  1908,  p.  960. 
