Am.  Jour.  Tharm.  1 
July,  1909.  / 
Syrups. 
319 
Sarsaparilla  (No.  20  powder)   200  Gms. 
Glycyrrhiza  (No.  20  powder)   15  Gms. 
Senna  (No.  20  powder)   15  Gms. 
Glycerin  .   125  c.c. 
Sugar   750  Gms. 
Oil  of  sassafras   0.2  c.c. 
Oil  of  anise   0.2  c.c. 
Oil  of  sweet  birch   0.2  c.c. 
Water,  a  sufficient  quantity. 
Add  the  glycerin  to  375  c.c.  of  water,  and,  having-  thoroughly 
mixed  the  ground  drugs,  moisten  with  225  c.c.  of  this  menstruum 
and  pack  in  a  percolator.  Allow  to  macerate  for  six  hours,  then 
percolate,  using  the  remainder  of  the  menstruum,  and  then  water 
till  600  c.c.  of  percolate  is  obtained.  In  this  dissolve  the  sugar  by 
heat.  Allow  to  cool,  strain,  add  the  oils,  thoroughly  incorporate  by 
agitation,  and  then  add  sufficient  water  to  obtain  1000  c.c.  of  product. 
Syrupus  Scill^e  Compositus  U.S. P. — In  order  to  critically  test 
this  official  formula,  samples  of  fluidextracts  of  squill  and  fluid- 
extract  of  senega  were  prepared  strictly  in  accordance  with  the 
U.S.P. 
The  object  of  evaporating  the  mixed  extracts  is  probably  to 
coagulate  the  albumin  as  well  as  to  remove  both  alcohol  and  the 
part  of  the  acetic  acid  that  is  not  fixed  as  potassium  acetate,  but  this 
can  be  accomplished  only  in  part  and  only  after  a  prolonged  heating. 
The  filtration  of  the  extracts  diluted  with  water,  using  talcum  as  a 
clarifying  agent,  is  tedious  and  unsatisfactory.  To  prepare  a  litre 
required  four  days  for  this  preliminary  operation.  The  finished 
product  is  not  satisfactory  and  soon  after  preparation  precipitation 
starts  and  continues  to  increase. 
The  following  formula  is  the  result  of  our  experiments : 
Squill  (No.  20  powder)   80  Gms. 
Senega  (No.  20  powder)   80  Gms. 
Antimony  and  potassium  tartrate   2  Gms. 
Acetic  acid    20  c.c. 
Glycerin    100  c.c. 
Sugar   700  Gms. 
Water,  a  sufficient  quantity. 
Mix  the  drugs  and  moisten  with  sufficient  of  a  mixture  of  the 
glycerin,  acetic  acid,  and  300  c.c.  of  water.  Place  loosely  in  a 
percolator,  cover,  and  allow  to  macerate  for  twenty-four  hours. 
Then  shake  down  so  as  to  pack  lightly  and  proceed  to  percolate, 
I 
