59° 
Progress  in  Pharmacy. 
{  Am,  Jour.  Ph&rm. 
|   December,  1909. 
bicarbonate  appears  to  lessen  the  poisonous  effects  of  acetanilid 
upon  the  heart. 
Cannabinol. — Max  Czerkis  reports  on  experiments  made  to  de- 
termine the  composition  of  cannabinol.  The  oxidation  as  well  as 
the  reduction  products  of  cannabinol  are  substances  mostly  resinous, 
not  crystalline,  and  not  readily  purified.  Cannabinol  C2H30O2  con- 
tains a  hydroxyl  group.  An  acetyl  group  can  be  added  and  on  care- 
ful nitration  a  trinitrocannabinol  can  be  produced. — Pharm.  Ztg., 
1909,  v.  54,  p.  767. 
Metabolized  Cod4iver  Oil. — The  Council  on  Pharmacy  and 
Chemistry  has  authorized  the  publication  of  a  report  from  the 
Chemical  Laboratory  of  the  American  Medical  Association  which 
indicates  that  Waterbury's  metabolized  cod-liver  oil  neither  contains 
nor  represents  any  appreciable  amount  of  cod-liver  oil,  and  that  the 
advertising  matter  that  has  been  published  in  regard  to  it  is  mis- 
leading and  therefore  fraudulent.  The  results  of  the  chemical 
examination  are  given  in  detail. — /.  Am.  Med.  Assoc.,  1909,  v.  53, 
pp.  1 201-1202. 
The  U.  S.  District  Attorney,  acting  upon  the  recommendation 
of  the  Secretary  of  Agriculture,  seized  thirty-six  cases  of."  Metabo- 
lized Cod-liver  Oil  Compound  "  in  Washington,  D.C.,  on  October  4, 
on  the  ground  that  it  was  misbranded  in  violation  of  the  Food  and 
Drugs  Act  of  June  30,  1906. — South.  Pharm.  Jour.,  1909,  v.  2,  p.  158. 
Chloral  monomenthol  and  chloral  dimenthol,  according  to  the 
Journal  de  Pharmacie  d3  Anvers  are  definite  combinations  obtained 
by  simply  melting  together,  on  a  water-bath,  the  required  amounts 
of  chloral  and  menthol. — Pharm.  Ztg.,  Berl.,  1909,  v.  54,  p.  569. 
Digalen. — This  is  said  to  be  "  soluble  amorphous  digitoxin  "  in 
a  mixture  of  distilled  water  and  alcohol.  The  average  single  dose, 
1  c.c,  is  said  to  contain  0.003  Gm.  of  digitoxinum  soluble  Cloetta. — 
/.  Am.  Med.  Assoc.,  1909,  v.  53,  p.  869. 
Ergothioneine. — C.  Tanret  has  isolated  a  new  alkaloid  from 
ergot  to  which  he  has  given  the  name  ergothioneine.  This  alkaloid 
is  soluble  in  8.6  parts  of  water  at  200  C,  very  soluble  in  hot  water, 
and  only  sparingly  soluble  in  strong  alcohol. — /.  de  Pharm.  et  de 
Chim.,  1909,  v.  30,  p.  145. 
Glycerin. — O.  T.  Joslin  discusses  the  comparative  cost  of  glycerin 
produced  by  the  Twitchell  process  and  that  recovered  from  waste 
soap  lye,  and  points  out  that  the  former  process  because  of  its 
economy  and  general  adaptability  is  destined  to  replace  the  older 
methods. — Jour.  Ind.  and  Eng.  Chem.,  1909,  v.  1,  p.  54. 
