OBSERVATIONS ON THE CUICHUNCHULLI. 
127 
of an application for it which Messrs. Casanova of that city- 
had made to their relation, Colonel Casanova at Guyaquil, 
from their anxiety to have the new remedy administered to 
one of the members of their respective family then afflicted 
with the Mai de San Lazaro. Immediately on receiving the 
Cuichunchulli, Senor de Aroche commenced giving it first to 
a person of colour, named Jacopo Puche, who had been long 
and greatly affected with the disorder just mentioned, and after- 
wards to Senor Angel Casanova, the individual above alluded to, 
and kept a journal of the principal occurrences he observed in 
each patient during their treatment. Of this journal a copy is 
before me, written and signed by that practitioner, which Ge- 
neral Montilla brought hither from Maracaybo in March last, 
when on his way to England as Envoy from the State of Ve- 
nezuela to the British Court, and very kindly put into my 
hands; and as I believe it to be the first authentic account 
drawn up by a professional man that has yet appeared of the 
effects of the Cuichunchulli in the Mai de San Lazaro, I con- 
ceive that it will be more satisfactory to the Profession gene- 
rally, that the whole of this interesting document, which is of 
but moderate length, should be submitted to them, than that it 
should be suppressed or even curtailed; I therefore give it en- 
tire. It is however proper here to observe, that the package 
received by Messrs. Casanova from their cousin, contained no 
stems, leaves, or flowers, but roots only, which agreed in ap- 
pearance with the description of the plant as above quoted 
from Velasco's history. 
DIARY OF THE EFFECTS OBSERVED IN PUCHE. 
This patient began to take the Cuichunchulli on the 17th of 
October, 1833, in daily doses of half a drachm of the plant in 
powder, diluted in two spoonsful of Sherry wine. Within a 
few hours of taking the first dose, there was a sensible increase 
in the urine and in the perspiration, accompanied with a disa- 
greeable feeling in the epigastric region. 
\Sih October. — He took an equal dose in the same vehicle 
