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SELECTED ARTICLES. 
testing the remedial power of whatever medicinal agent might 
be employed. 
" It was in this state that she began to take the Cuichun- 
chulli, which was given in the powder mixed with wine in 
doses of half a drachm, afterwards increased to two drachms; 
and she took in the whole ten drachms, which, though scanty, 
was all that could be obtained for a trial. The sensible effects 
were, a formication over various portions of the skin, but 
especially in the lower extremities, nausea more or less consi- 
derable and frequent, increased spitting like salivation, an open 
state of the pores, and even some perspiration, giddiness or 
vertigoes, a copious flow of turbid urine depositing a sediment, 
and whitish bilious evacuations. Of these several effects the 
ptyalism continued for many days after the medicine was ex- 
pended. The result has been that the patient has experienced 
some marked alterations in her system, and a favourable 
change in the intensity of some of the symptoms. She has 
felt pains and tension in the hypogastrium, accompanied with 
a serous discharge tinged with blood, indicative as it were of 
menstruation, which had not yet appeared, although she is 
now 18 years old. She finds that her breasts, previously 
obliterated, are becoming painful and enlarging; her counte- 
nance is now cheerful, the colour of her skin lighter, the ears 
are reduced in size and no longer covered with scales; her 
voice is clear, the corroding ulcers on her fingers have healed, 
and her hands have acquired sufficient pliableness and sensi- 
bility to enable her to use her needle. Two small tumours 
which she says that she had on the right shin, probably in the 
periosteum, have disappeared. In short, she performs all her 
functions with cheerfulness, ease, and promptness, particularly 
when moving about." 
Such are the cases related by Senor de Aroche and Dr. Ar- 
velo; and although both their trials with the Cuichunchulli 
were cut short by insufficiency of the medicine supplied, they 
serve at least, if they may be relied upon, to attest its highly 
beneficial action in two of the three patients, Puche and Miss 
Macpherson. Yet, if these trials be compared with that of 
