190 
ORIGINAL COMMUNICATIONS. 
Paris, &c. stating that at the request of Mr. Delondre he had 
visited his manufactory of Sulphate of Quinine at Nogent sur 
Marne, and had taken for specimens of one ounce each from 
a lot of two thousand ounces packed up for New York. 
" The four specimens were marked 1, 2, 3, 4, and subjected 
to the following experiments: 
1. "The quinine was subjected to a heat of 212° F. for 
three hours to determine the quantity of water of crystalliza- 
tion. 
2. "Another portion was calcined till all organic matters 
were destroyed, to ascertain if it contained any salts or other 
inorganic substances. 
3. " It was treated with alcohol at 36°. 
4. " It was subjected to the action of water to which a small 
quantity of sulphuric acid had been added. 
5. "A solution of the Sulphate was decomposed by means 
of ammonia, thus giving a precipitate of Quinia; and the liquid 
was examined to ascertain if it contained any foreign substance, 
as sugar, &c. 
" The result of these experiments was as follows. 
"Water of crystallization in the 100 parts, 
1. 12. | 2. 12. | 3. 11. | 4. 12. 
"Theory indicates 15 to 16 per cent, of water of crystalli- 
zation in this salt; Berzelius, v. p. 159 ; Dumas, v. p. 
747. This difference may be^ explained by supposing that 
some portion of the salt had effloresced. 
The calcination of a 1000 parts gave of incombustible resi- 
due: 
1. 8. | 2. 8. | 3. 4. | 4. 6. 
"The four specimens when treated with alcohol, were per- 
fectly dissolved, leaving no appreciable residue. 
"They were also completely soluble in water to which a 
little sulphuric acid had been added. 
" Finally, the aqueous solution decomposed by ammonia, 
I 
