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SELECTED ARTICLES. 
quantity daily in the same proportion. When fourteen grains 
had been taken, the patient complained of pain in the throat; 
she rested well, but talked in her sleep, which she had not 
previously done; she also experienced sudden but transient 
cramps in her legs. When the dose was increased to sixteen 
grains, she suffered much from the pain in the throat, had dis- 
tressing and frightful dreams, a sensation of weight in the 
head; but there was no dilatation of the pupil, and no irregu- 
larity of the pulse; the rheumatic pains were, however, re- 
moved. On discontinuing the remedy, all the above symp- 
toms disappeared in a short time. 
The second trial was on a young man, aged 20, affected 
with phthisis. After taking sixteen grains, he complained 
that his sleep was not as tranquil as formerly, but no other 
change was produced. 
In a third patient, aged 44, also consumptive, the first 
symptoms of the pain in the throat were after the dose had 
been increased to ten grains; at fourteen they rapidly in- 
creased, with the addition of some headache, but no dilatation 
of the pupil; at sixteen, some trembling of the hands, sleep 
tranquil. On augmenting the dose, the trembling became 
greater, but no change was produced in the disease. 
Insoluble green fecula of hyoscyamus. A single trial was 
made with this on a patient, aged 22, convalescent from a 
pneumonia. Ten grains produced no effect, twelve caused a 
slight disturbance of the sight; and the sleep was somewhat 
disturbed, but no unpleasant dreams. 
Green fecula of hyoscyamus by coagulation. It was 
tried on a patient affected with an habitual headache. The 
dose was augmented in the ratio of two grains each day. 
After ten had been administered, the sleep became disturbed, 
but there was no dilatation of the pupil; after fourteen grains, 
the patient slept better, but complained of uneasiness in his 
legs; after eighteen grains, he experienced nausea, want of 
sleep, and sense of weight in the head. On discontinuing the 
medicine, the symptoms soon disappeared. 
