ON PHLORIDZINE. 
241 
When subjected to analysis, by the method of Leibig modi- 
fied by Mitscherlich, 0,5135 grammes gave per 100 parts 
Carbon 59.905 
Hydrogen 5.569 
Oxygen 43.526 
0.812 grammes gave Carbon 51.10 
Hydrogen 5.77 
Oxygen 43.13 
On the other hand Dr. De Koninck found the combination of 
phloridzine with oxide of lead, gave 57.26 of oxide, and 42.74 
of phloridzine, and hence obtained, as the atomic weight of the 
latter, 1040.88. If it be admitted that phloridzine is formed of 
C 14 H 18 O 3 . 2082.48 
,the atomic number would be — = 1041.24. 
The preparation of this substance is very simple. The 
fresh bark of the root of the apple tree, (the dry bark contains 
scarcely any,) is to be boiled for two hours with sufficient 
water to cover the bark; the decoction is to be decanted, and 
a second one made by the addition of more water. On uniting 
the two decoctions and permitting them to stand for twenty- 
four hours, a deposit of phloridzine in granular crystals will 
take place. These are to be treated with distilled water and 
animal charcoal to purify them. An additional quantity is 
obtained by evaporating the mother waters to ±. At this de- 
gree of concentration all the phloridzine is deposited. This 
method will afford about T |^-. There is another and a better 
plan which will give T f q. It consists in digesting the fresh 
root in weak alcohol at a temperature of 120° for about eight 
or ten hours, distilling off the greater portion of the alcohol, 
and crystallizing the residue. 
Phloridzine has great analogy to populine, but at the same 
time has many distinguishing characteristics. Thus, it is solu- 
ble in 1000 parts of cold water, whilst populine requires 
2000; it produces a precipitate with the tritosulphate of iron 
and subacetate of lead, whilst populine does not. When 
treated with nitric acid it does not, like that substance, afford 
a bitter, but is converted into oxalic acid. Like populine, 
VOL. II. — no. ni. 31 
