ON THE TOXIC CONSTITUENTS IN THE BARK OF ROBINIA PSEUDACACIA L. 3839 
Preliminary experiment. 
To ascertain what symptoms can be produced by the fresh bark, the fresh 
material, sent from the Hokkaidö district, was chopped fine and given, mixed 
with bran of wheat, to two horses, whose usual evening and meruing rations 
‚previous to the experiment were discontinued. The rise of temperature after 
the administration of the bark was 2°C. in one horse and 1°C. in the other, 
the other symptoms being almost the same in both. 
Example. June 13th, 1916 
Name of horse Ömi. 9 years old. Body weight 450 kilos. 
Time JR R. 12? Symptoms 
12°-13/ | 386 | 14 60 Normal. 
1°-0/ | ,— —_ — .200 gms. of the bark given. 
4 I — —_ — All eaten up. 
2°-15/ | — — _ Defecation (faeces 50 boli, normal consistence). 
20/ — _- — Fr (faeces 12 boli, normal consistence). 
407 |, — _ — > (faeces 25 boli, a little soft, mucus adhering). 
42/ — — — = (faeces 20 boli, slightly soft), salivation and nasal 
discharge. 
52’; — —_ — Defxcation (feeces 25 boli, like cattle faces), beginning to 
paw, a little uneasy and excited. 
3_0/ 3931| 34 64 Sometimes pawing, peristalsis becomes weak, conjunctival hy- 
peremy, saccral reilex slightly dull. 
30/ a= a a2 Hind part of body becomes a little weak. 
°_0/ 39.3 | 18 60 Defzecation (about 2 litres, muddy, having unpleasant smell, 
mixed with mucus), pulse weak, abdominal type of respira- 
tion, peristalsis very weak, indifferent to flies. gathering on 
the skin, legs feel cold. 
o_(/ 39.5 | 20 60 Peristalsis a little strong at right side, but weak at left. 
tty ee = a Defzecation (1 litre, like cattle faeces), a metallic sound in 
peristalisis. 
°_Qr 395| 14 66 Defzecation (0.5 litres, very soft and mixed with much pseud- 
membrane), salivation, strong hyperemia of visible mucous 
membranes, tearing. 
Oly 39.5 14 60 Peristalsis being excited, penis lowers. 
an ce, — — Defxcation (1 litre, muddy, mixed with many undigested 
grains of barley), ramblings to be heard. 
