350 BUHACHIRO TASAKI AND USHIO TANAKA. 
Example. July 11th, 1916. 
Rabbit No. 5. Body weight 3115. grams, female. 
Time Temperature Symptoms 
2° 30/ 39.1 Normal, robitin 1gm. (as 10 ccm. aqueous solution) intraven- 
ously, 
35! _ Head shakes, ears half hanging down. 
45! 39.3 —_ 
55/ 40.1 _ 
Sb 5% 41.0 Depressed. 
20! = Evacuation. 
30! = Hind part of body staggering, micturition, dyspnea. 
43/ 41.8 = 
4° Of 41.5 = 
30’ _ Defzecation. 
40! _ Strong difficulty in breathing, great depression, lies down 
4° 50/ Stand up, respiratory sound very high. N 
5° 30! 39.2 Thenceforth no great change of symptoms, died 39 hours after 
the injection. 
TABLE II. 
Injection of robitin to rabbits. 
rer | Se =.. 
Date E : 3 = Material Re; : 
24/V1/’16 1 2.585 Robitin intravenously "| ww 
10/VII/’17 2.325 > ” it 
” 4 | 3.115 er hypodermically - 
12/VIL He + As intravenously Er 
” 3 | 2.325 I » ae 
22/V1/’16 2 | 3.435] Aqueous extract of the bark. hypodermically Er 
Remarks : 
For explanation of marks of results see Table I. 
III. Horse. 
If 0.0015 grams of robitin per 1 kilo. body weight is injected intravenous- 
ly into the horse, we observe all the typical symptoms, and with 0.003 grams 
the horse falls into agonial stage, 0.05 grams being its lethal dosis. 
