M. Sawyer, L. Baumann, and F. Stevens 109 
to neutralize more acid (545 cc.) than the surplus of ammonia 
(480 cc.). 
Fitz, Alsberg, and Henderson® and others have pointed out 
the increased elimination of acid phosphates during periods of 
acidosis. This may account for part of the increased excretion 
of sodium, potassium, and phosphorus during the period of high 
fat feeding. 
The phosphorus loss of the older child, with the more moder- 
ate acid production, was less than one-half that of the other. 
Calcium was actually retained. The loss of sodium and chlorine, 
however, was more marked. The diminished excretion of so- 
dium chloride, by the younger child, with the more marked acid 
production, may possibly be explained by the observation of 
Fischer’? that acidosis is associated with a decreased sodium 
chloride elimination. 
The above observations, largely confirmatory in nature, indi- 
cate that a considerable loss of minerals, especially phosphorus 
and calcitwm, may accompany short periods of increased acid pro- 
duction in children. The excretion of these elements, in the two 
cases studied, varies directly with the severity of the acidosis. 
The pronounced loss of nitrogen during the high fat period is a 
field for further investigation. 
In conclusion, we wish to thank Drs. Dean, Steindler, and 
Beifeld for their cooperation, and Miss Helen Mougey for the 
care exercised in the preparation of the diets. 
* Fitz, R., Alsberg, C. L., and Henderson, L. J., Am. J. Physiol., 1907, 
xviii, 113. 
10 Fischer, M. H., J. Am. Med. Assn., 1915, lxiv, 325. 
