J. H. Austin and L. Jonas 97 
Experiment 3 B.—Oct. 28, 10.50 a.m. Given 100 cc. of 5 per cent so- 
dium chloride solution by stomach tube. 11.55 a.m. Same dose of so- 
dium chloride repeated. Catheterized. 12.30 p.m. Bled 20 ec. 1.05 
p.m. Catheterized. 167 cc. of urine (70 minutes). N, 6.8; D, 53.3; 
E, 15.5. 
Experiment 4.—Uranium nephritis. For 5 days (Oct. 29 to Nov. 3) on 
diet of milk, 1 quart, and one dog biscuit daily. Water ad libitum. 
Oct. 30. Given uranium nitrate, 0.02 gm. subcutaneously. 
Nov. 4. Shows a moderate cloud of albumin in urine. 
Experiment 4 A.—No food or water since previous day. 
Nov. 4, 12.03 p.m. Catheterized. Given 100 ce. of distilled water by 
stomach tube. 12.37 p.m. Bled 12 ce. 1.25 p.m. Catheterized. 25 cc. 
of urine (82 minutes). N, 7.4; D, 0.13; E, 0.3. 
Experiment 4 B.—Nov. 4, 1.25 p.m. Given 100 ce. of 5 per cent sodium 
chloride solution by stomach tube. 2.32 p.m. Same dose of sodium 
chloride repeated. Catheterized. 3.10 p.m. Bled 24 cc. 3.42 p.m. 
Catheterized. 35 cc. of urine (70 minutes). N, 7.7; D, 0.78; E, 1.04; 
blood urea N, 39. 
Dog II.—Female, weight 16 kilos. 
Experiment §.—Ordinary diet. Diet of milk, 1 quart, and one dog 
biscuit daily beginning Dec. 27. Water ad libitum. 
Experiment 5 A.—No food or water since previous day. Dec. 29, 
11.07 a.m. Catheterized. Given 100 cc. of distilled water by stomach 
tube. 11.52 a.m. Bled 25 cc. 12.25 p.m. Catheterized. 25 cc. of 
urine (78 minutes). N, 5.9; D, 0.67; E, 1.46; X, 0.0129; blood urea N, 14. 
Experiment 5 B.—Dec. 29, 12.25 p.m. Given 100 cc. of 5 per cent so- 
dium chloride solution by stomach tube. 1.50 p.m. Same dose of so- 
dium chloride repeated. Catheterized. 2.32 p.m. Bled 35 ce. 3.10 
p.m. Catheterized. 59 cc. of urine (80 minutes). N, 6.7; D, 17.1; E, 
16.1; X, 0.0142. 
Experiment 6.—High salt diet. Dog continued on the same diet of milk 
and dog biscuit. For 4 days (Jan. 2 to 5) received in addition sodium 
chloride as follows: Jan. 2 and 3, 130 cc. of 5 per cent sodium chloride so- 
lution by stomach tube; Jan. 4 and 5, 200 cc. of same. Water ad libitum. 
Diarrhea beginning Jan. 3. 
Experiment 6 A.—No food, water, or salt since previous day. 
Jan. 6, 11.00 a.m. Catheterized. Given 100 cc. of distilled water by 
stomach tube. 11.35 a.m. Bled 30 cc. 12.25 p.m. Catheterized. 9.5 
cc. of urine (85 minutes). N, 6.0; D, 0.56; E, 3.5; blood urea N, 10. 
Dog III.—Female, weight 14 kilos. 
Experiment 7.—Ordinary diet. Placed on a diet of milk, 1 quart, and 
one dog biscuit, beginning Dec. 27. Water ad libitum. | 
Experiment 7 A.—No food or water since previous day. 
Jan. 2, 11.40 a.m. Catheterized. Given 100 cc. of distilled water by 
stomach tube. 12.25 p.m. Bled 20 ce. 1.10 p.m. Catheterized. 5 cc. 
of urine (90 minutes). N, 6.0; D, 0.1; E, 1.2; X, 0.0132. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY, VOL. XXXIII, NO. 1 
