S. Kuriyama | 209 
TABLE II. 
The Epinephrine Content of the Adrenals of Thyroid-Fed Rats. 
on Weight of ae 
of body an tine at | Weight of fen Epineph- ae as 
ons so Niibecaecs end of ex- ee 100 2m. of Paiter ee es of beds 
periment. es ett a taiy adrenals. | adrenal. eight 
weight. 
Series A. Desiccated thyroid; 1 gm. per day for 4 days. 
gm. mg. mg. mg. mg. mg. 
IT) M. | —17.2| 276.4} 42.0 15.2 0.095 | 2.26 0.034 
12 —18.5 |. 254.2)) 34.1 13.4 0.092 | 2.70 0.036 
126 ig Poe —23.0 | 244.0] 34.8 14.3 0.093 |; 2.67 0.038 
DV Gy a —14.9} 126.9] 28.1 22.1 0:059 ; 2.10 0.047 
Voy. ars —22.9 | 125.4) 30.5 24.3 OP057)) hse 0.645 
VI; F. | —17.0| 267.8] 44.9 16.8 0.092 ; 2.05 0.034 
0 & i i he —18.8 |} 189.9) 48.3 25.4 0.106 | 2.20 0.056 
VIII as —17.3 | 182.8 | 43.4 23.7 OLlils)) 2.86 0.061 
1f-« by —19.1 178.6 | 64.5 36.1 0.119 | 1.85 0.067 
xX es —18.8| 178.1 | 438.4 24.4 0.084 | 1.94 0.047 
XI 17S 113.4) 44.3 25.5 O01 2.28 0.058 
Average.o 2! ys. 14 199.8 | 41.7 21.9 0.092 | 2.23 0.048 
Series B. Desiccated thyroid; 0.1 gm. per day for 23 days. 
1? oM. aos es0s od be OULO ASe/ OPLOL FP 2.02 0.058 
Tis —5.4] 231.6] 41.5 Lg 0.098 | 2.36 0.042 
96 ee —10.0 | 221.0 | 46.6 TAA OAZGM H2a70 0.957 
LO eRe ee Po i Sha Ce OR 2 hae 0.0711. 1.96 0.034 
Vato, —4.8| 198.4] 50.6 25.5 0.142 | 2.81 0.072 
ELLs ae +0.9| 176.4 | 38.4 21.8 0,082 | 2.14 0.047 
Whi as —2.6| 149.4} 37.8 25.3 0.083 | 2.20 0.056 
ELT 21.5 —14.1 | 144.6) 42.1 29.1 OLOSD 211292 0.056 
Average. i.%,. 4... m.2}2 199.9 |. 42.9 22.1 Dee 2.26 0.050 
As the epinephrine content of the adrenals of normal animals 
(mg. of epinephrine per gm. of the gland), Folin and his co- 
workers? found 2.41 to 3.08 mg. in the sheep, 2.04 to 2.33 mg. 
in the dog,‘3.33 to 3.52 mg. in the calf, 1.22 to 1.52 mg. in the 
young cat, and Herring found 1.25 to 2.22 mg. in the cat, and 
1.47 to 2.97 mg. in the albino rat. In my experiments this 
value in albino rats averaged 2.20 mg. The maximum was 3.44 
THE JOURNAL OF BIOLOGICAL CHEMISTRY, VOL. XXXIII, NO. 1 
