Y.,Henderson and H. W. Haggard 349 
| Experiment 4.—Dog, male, 10 kilos. Light and irregular ether for 210 
minutes, with spontaneous recovery toward normal during following 90 
minutes. LHquilibrating air 5.7 per cent COs. 
Hespire: Blood CO. 
Time. Condition. tions per 
cpr Content. | Capacity. 
vol. per cent| vol. per cent 
9.30 a.m. 20 50 53 
9.45. * Ether started. 
10:00" “ 82 
TO-ta: - = 42 50 
10.80;- * 68 
10.45 * 36 47 
ERLOO 66 
Hiftas 37 44 
Tice. 69 . 
Teaoe 36 41 
1200 59 
Too =" 40 38 
12.30 << 60 
1.15 p.m. 35 38 
16205; “ Ether stopped. 
1: ed 43 39 
PAs ase 49 43 
yi lead 47 46 
Day) Ss Animal in good condition. 
Evidently in the foregoing experiment the decrease of the CO» 
capacity (alkaline reserve) was spontaneously reversible from the 
low level reached. 
The first part of Experiment 5 was similar to the preceding 
experiment. After the CO, capacity had been reduced to 39 in 
this case however, instead of discontinuing the ether the amount 
administered was increased to a maximum just short of causing 
respiratory failure. This condition was continued for 80 min- 
utes: Under the depression of respiration thus caused the alveo- 
lar CO, was of course increased. The CO, content of the blood 
rose to 67 and the CO: capacity was raised to 54; that is, slightly 
above normal. The animal died soon after, probably from an 
insufficiency of oxygen. 
