356 CO, Capacity of Blood. III ‘ 
fact that, as reported, shock occurs in only a minority of the wounded. 
Furthermore overventilation quickly results in a numbing of sensation,— 
an almost anesthetic condition as regards consciousness, and yet the 
excessive breathing may continue. 
Method. 
In general the methods employed were similar to those in the 
preceding papers of this series. The animals were however given 
an intramuscular injection of chloratone dissolved in alcohol. 
At the outset of each experiment they were also etherized for a 
few minutes. 
The apparatus with which the excessive artificial respiration 
was administered is shown in Fig. 1. It consisted of two rotary 
air blowers belted to a shafting (not shown) so that one forced air 
toward a Y tube tied into the trachea and the other sucked air 
from it. Escape valves were connected with each side to prevent 
the pressures either positive or negative ever exceeding 30 cm. 
water column. By means of a hand lever the Y tube in the 
trachea was opened alternately to pressure and suction. 
EXPERIMENTAL. 
In a control experiment without artificial respiration it was 
found that chloratone itself in the dosage employed has no 
marked effect upon either the CO, content or CO, capacity of the 
blood. It is well known that dogs under chloratone have a low 
arterial pressure. 
Experiment 1.—Control. Dog, male, 19 kilos. Chloratone anesthesia. 
Equilibrating air 5.5 per cent COd. 
Blood CO2. 
Time. Condition. 
Content. Capacity. 
vol. per cent vol. per cent 
10.30 a.m. Normal. 48 49 
10.45. * Chloratone administered, 4.8 
gm. 
14 oD wae 46 48 
1.35 p.m. 47 46 
2.859% 48 46 
