Y. Henderson and H. W. Haggard 367 
around the wrist was packed with cotton to prevent loss of heat 
or the escape of a loop of intestine. The clenched hand was 
moved rapidly 50 or 60 times a minute so as to bring the knuckles 
with a downward and forward motion upon the duodenal end of 
the stomach. The result was vigorous respiration on the part of 
the subject. Several times there was vomiting. The animal 
was kept upon a’ warm plate and there was no fall of rectal 
temperature. Any consciousness of pain was prevented by the 
morphine administered. 
In Experiment 2 trauma and excessive breathing were pro- 
duced in this way. The animal was, however, made to breathe 
Experiment 2.—Dog, male, 12 kilos. Gastric manipulation, while the 
animal breathed CO, and later without CO2. Equilibrating air 5.55 per 
-eent COs. 
eo 3 Blood CO». : 
; oe Brak aa Arterial 
Time. Condition. aE E 5 5 Zr ea ee es zo saee 
(ahi t=: He) tent. | pacity. 
p.m. per cent ea, ihr, mm, 
1.45 | Normal. 26 48 50 
2.00 | Morphine, 0.24 gm. 
215 16 108 
2.45 15 67 60 110 
2.53 | CO. started. 6.8 
3.05 | Abdominal incision. 19 120 
3.15 | Gastric manipulation started. 56 120 
3.30 54 120 
3.45 | Vomited. 43 5.8 | 56 50 130 
4.15 44 7.0 128 
4.45 37 fl 9.09 56 116 
4.53 | Manipulations stopped. : 
5.10 | COz stopped. 
5.15 in 
5.30 7 0 41 ; 49 106 
6.30 9 0 46 47 | 106 
6.45 | Gastric manipulation. 34 108 
7.05 | Manipulation stopped. 34 . 
7.15 9 36 36 70 
7.30 | Dog dead. 44 
air containing a sufficient amount of CO, to prevent loss. 
From the protocol it will be seen that after an hour and 38 minutes 
