STUDIES OF THE BLOOD FAT AND LIPOIDS OF THE 
DOG BEFORE AND AFTER THE PRODUCTION 
OF EXPERIMENTAL ANEMIA. 
By HARRY DUBIN. 
(From the John Herr Musser Department of Research Medicine, University 
of Pennsylvania, Philadelphia.) 
, 
(Received for publication, January 5, 1918.) 
By the use of the nephelometric and colorimetric methods of 
Bloor,! blood fats have been estimated in one dog and the zesu! - 
show that in trypanosome anemia, the total fats are increascu 
while the lecithin and cholesterol are decreased. These results 
are in accord with the findings of Bloor? in pernicious anemia 
associated with carcinoma of the stomach. 
Fats and Lipoids of Dog’s Blood before and after Infection with Trypanosoma 
equiperdum. 
Total fat. Lecithin. Cholesterol. 
Period. Date. ri . Bc 3 -s * Remarks. 
22 g oe g ES g 
o,f n og n Og a 
ae 8 2.0 x Rafe) 3 
= Ay = A, = Ay 
1917 gm.* | gm gm qm gm gm 
Normal. Apr. 26 | 0.55} 0.56) 0.43) 0.40) 0.25) 0.30} Apr. 24, hemoglo- 
bin, 99. 
May 2 | 0.53} 0.57) 0.37) 0.35} 0.22) 0.27) Infected May 4. 
Anemic. May 16 | 0.68] 0.69) 0.38) 0.30} 0.22} 0.19) May 18, hemo- 
globin, 56. 
1S) 0.200275) 029) 02277 0: 201, 0-28 
ee 22 Used era) O. od) O-20h0) 4 Onl 2 
* All figures represent gm. per 100 ce. of blood. 
1 Bloor, W. R., Studies on blood fat. II. Fat absorption and the blood 
lipoids, J. Biol. Chem., 1915, xxiii, 317; The determination of cholesterol in 
blood, 1916, xxiv, 227; Fat assimilation, xxiv, 447. 
2 Bloor, The distribution of the lipoids (‘‘fat’’) in human blood, J. 
Biol. Chem., 1916, xxv. 577. : 
Olt 
