COMPARISON OF THE GLUCOSE AND CHOLESTEROL 
CONTENT OF THE .BLOOD. 
By F. H. McCRUDDEN anp C. 8. SARGENT. 
(From the Robert B. Brigham Hospital, Boston.) 
(Received for publication, January 4, 1918.) 
The association of hyperglycemia and hypercholesterolemia in 
diabetes! ? and of hypoglycemia and hypocholesterolemia in pro- 
gressive muscular dystrophy,’:* pointing to some kind of phys- 
iological relationship between glucose and cholesterol, suggested 
that there might be a parallelism between the amounts of the two 
substances in the blood. But this op peat not to be the case 
(Table I and Chart 1). 
Glucose was determined by the method of Lewis and Benedict,*> and 
cholesterol by the method of Autenrieth and Funk.’ Analyses were made 
in duplicate or triplicate. 
1 Bloor, W., The lipoids (‘‘fat’’) of the blood in diabetes, J. Biol. Chem.., 
1916, xxvi, 417. 
2 Joslin, KE. P., Bloor, W. R., and Gray, H., The blood lipoids in diabetes, 
J. Am. Med: Assn., 1917, |xix, 375. 
3 McCrudden, F. H., and Sargent, C. 8., Hypoglycemia and progres- 
sive muscular dystrophy, Arch. Int. Med., 1916, xvii, 465. 
4 McCrudden and Sargent, Chemical changes in the blood and urine in 
progressive muscular dystrophy, progressive muscular atrophy, and 
myasthenia gravis, Arch. Int. Med., 1918, xxi, 252. a 
5 Lewis and Benedict’s method (J. Biol. Chem., 1915, xx, 61) as modi- 
fied by Myers and Fine (Myers, V. C., and Fine, M.S., Chemical Compo- 
sition of the Blood in Health and Disease, New York, 1915.) 
6 Authenrieth, W., and Funk, A., Ueber kolorimetrische Bestimmungs- 
methoden: die Bestimmung des Gesamtcholesterins im Blute und in 
Organen, Miinch. med. Woch., 1913, lx, 1248. 
