W. Pitz 475 
kernel, due to its formation of pasty feces, when fed rats was 
also noted by McCollum, Simmonds, and Pitz (6), in their in- 
vestigation of the dietary deficiencies of the oat kernel. 
Animals that received corn, wheat, or barley and milk were 
protected from scurvy by the addition of lactose to the ration. 
With these grains, however, 10 per cent of lactose when added 
to the grain was just as effective in preventing scurvy as was 20 
per cent of lactose when fed with oats. 20 per cent of lactose 
when fed with corn, wheat, or barley caused abnormal fermenta- 
tion in the tract of the animal and caused the abdomen to be 
greatly distended with gas. 
These results show that scurvy can be produced in the guinea 
pig by feeding a ration of unmilled grains and milk. 
I wish to thank Professor E. B. Hart for the many suggestions 
which he offered and especially for his suggestion of the feeding 
of lactose and the various grains. 
BIBLIOGRAPHY. 
—_ 
. McCollum, E. V., and Pitz, W., J. Biol. Chem., 1917, xxxi, 229. 
2. Hull, T. G., and Rettger, L. F., Centr. Bakteriol., 1te Abt., Orig., 1915, 
Ixxy, 219. 
3. Hirschler, A., Z. physiol. Chem., 1886, x, 306. 
4, Lusk, G., Elements of the Science of Nutrition, Philadelphia, 3rd edi- 
tion, 1917, 365. 
5. Jackson, L., and Moore, J. J., J. Infect. Dis., 1916, xix, 478. 
6. McCollum, E. V., Simmonds, N., and Pitz, W., J. Biol. Chem., 1916, 
xxix, 341. 
