The future of mosquito-borne diseases will depend on the improvements and implementation of chemotherapy and vaccination, as well as on biological and integrated control measures. Bacillus thuringiensis H-14, B. sphaericus, Lagenidium giganteum and other fungi are promising biological mosquito control agents. Other control measures include parasitoids, nematodes, larvivorous fish, Toxorhynchites mosquitoes, insect viruses, growth hormones, sex attractants, natural products, sanitation, and water management. Vector control should be combined with training of personnel and carried out on an international scale.